Cook pasta to al dente. Drain and rinse.
In saucepan, melt butter. Whisk in flour until smooth. Over medium heat, add milk and cream whisking constantly until incorporated. Reduce heat to medium low and continue to whisk every few minutes until thickened. Add mustard, pepper and cheeses. Add sauce to cooked pasta and place in large casserole dish. Combine 5 tbs. melted butter with 1 1/2 cups Panko bread crumbs and sprinkle on top.
Cover with foil. Bake at 350 degrees for 30 minutes. Remove foil and brown top.